Numerous factors contribute to the ability to conceive a child. Many of these factors are out of control which prevent couples from conceiving. The inability of a couple to conceive is termed as infertility. Both, men and women, struggle with infertility. about one-third of all infertility problems are due to male factor infertility. One of the common infertility issues in men is Azoospermia.

What is Azoospermia?

Normally, men have up to 300 million sperm in their semen. However, when there is no sperm conceiving a child for such couple can become difficult. In normal men, testicles produce sperm which flows through epididymis, vas deferens, to seminal ducts where it mixes with the fluid and form semen. The absence of sperm in semen is called Azoospermia.



What is Obstructive and Non-Obstructive Azoospermia?

Obstructive and Non-obstructive Azoospermia are two broad types of azoospermia.

  • In Obstructive Azoospermia, sperm is being produced normally but there is some problem which prevents the sperm from travelling out of testes.
  • Non-Obstructive Azoospermia refers to a set of disorders which causes the production of abnormal sperm. In non-obstructive azoospermia, either the sperm production is decreased or the body produces no sperm at all.
  • Testicular Non-Obstructive Azoospermia is when something is preventing testes from creating normal sperm. It can be caused due to a number of reasons such as, cancer, varicoceles, genetic syndromes or incomplete development.

What is Azoospermia Treatment?

Obstructive Azoospermia Treatment: Obstructive Azoospermia can be treated through either of the following ways depending upon each case;


Men who have had undergone vasectomy in the past can undergo vasectomy reversal to conceive.


In microTESE, testicular tissue with sperm is extracted with a needle or by making a small incision. The retrieved sperm can be used for conception through IVF / ICSI.


Sometimes, men have a narrow foreskin which prevents the ejaculate from coming out. In such cases, circumcision can be helpful to remove the foreskin to conceive naturally.

Transurethral Resection of Ejaculatory Duct (TURED):

Men suffering with ejaculatory duct obstruction can undergo transurethral resection which will remove the blockage and allow the sperm flow to the natural channels. .

Surgical Correction:

Scarring due to STIs can block the sperm inside the ducts. This can be corrected surgically or through endoscopy.

Non-Obstructive Azoospermia Treatment

Over a decade ago, there was not much hope for those suffering with non-obstructive azoospermia. However, with advancements in diagnostic procedures and testing, non-obstructive azoospermia treatment is equally possible. The treatment begins with semen analysis and blood work. Finally, any of the following treatment approach can be used for treatment;


When non-obstructive azoospermia is caused due to low bioavailable testosterone then medicines such as, clomiphene citrate, are used to return testosterone to normal range. Most of the time, the results have been successful. After medications, semen analysis is done again. Moreover, medications increase the chances of finding sperm during micro-surgical testicular sperm extraction (microTESE).


MicroTESE: For men who have normal testosterone levels, microTESE is recommended. About 60% of the time, microTESE is successful followed by IVF / ICSI.

Australian Concept Infertility Medical Center is the most successful infertility clinic of the country which offers the best azoospermia treatment in Pakistan. It has numerous clinics present in all the major cities offering azoospermia treatment at competitive rates with highest success rate in Pakistan.


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