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What is Preimplantation Genetic Testing?

Preimplantation genetic testing, or PGT, is a type of genetic testing that offers significant benefits. It allows embryologists to test embryos for the presence of any genetic hereditary disease, separating the affected embryos from normal ones. IVF doctors then use these normal and healthy embryos for embryo transfer and pregnancy. This test is a game-changer, helping to prescreen embryos and ensuring a healthy pregnancy. It not only saves couples from many unwanted circumstances for their children and themselves but also increases the chances of a healthy pregnancy. On the other hand, abnormal embryos may often result in either failed implantation or miscarriage during later months, highlighting the importance of PGT in ensuring a successful pregnancy.

PGT Process and Indications Step-By-Step:

The definition of preimplantation genetic testing is to test embryos before implantation. Therefore, the PGT test includes making embryos in the laboratory through in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). IVF is where infertility specialists take human eggs and sperm from the body of a couple and prepare embryos in the laboratory. Then, they use these embryos for testing, and embryo transfer follows.

PGT Process

PGT Procedure

Indications for PGT:

Genetics Indication

What are PGT-A and PGT-SR?

PGT-A is a type of PGT that detects chromosomal aneuploidies. An aneuploidy means the presence of an extra chromosome or the absence of a chromosome in an embryo. The average chromosome number in a human embryo or normal human cell is 46. Any change to this number can cause a disease known as aneuploidy. For example, Down Syndrome is a widespread disease where people face delayed milestones, mental retardations, and multiple other aspects. An extra copy of chromosome 21 in Down Syndrome causes all these symptoms.

PGT-SR is a type of PGT that detects structural arrangements in chromosomes. There is a situation when one or a group of genes in a chromosome can change their position. It may result in a carrier state or diseased persons. A carrier state is when a person himself does not manifest symptoms of a disease but can transfer the tendency of that disease to the next generation. The diseases related to this group include malformations of the part of the body, neuropathies (brain developmental diseases), and many other conditions.

Who Needs PGT Testing?

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Success Rate of PGT Testing:

Preimplantation genetic testing IVF has better success rates than simple IVF. The success rate of regular IVF without PGT is up to 40 percent, a maximum below the age of 35. PGT testing increases this rate to more than 60 percent below 35. It is because PGT separates healthy and genetically sound embryos for transfer, which have maximum chances for implantation and minimum chances of miscarriages.

How many rounds of PGT attempts are allowed?

The number of PGT attempts can vary from patient to patient, depending on the clinical practices of an IVF center and the patient’s reasons for going for PGT.

PGT Cost in Pakistan

The cost of PGT depends on different factors, such as the facility providing it, the number of attempts, the type of PGT, the prescreening of patients, and the location of the IVF clinic. Overall, PGT is costly, but its advantages are more valuable than the cost. Preimplantation genetic testing prices are high internationally as compared to Pakistan. Australian Concept Infertility Medical Center is the center for excellence in assisted reproductive technologies such as PGT, IVF, and ICSI and provides PGT services at affordable prices compared to international rates.

Cost PGT

Best IVF Clinic for PGT Test in Pakistan:

Australian Concept Infertility Medical Center is Pakistan’s best infertility center for PGT. We have more than 26 years of experience in assisted reproductive technologies such as IVF, ICSI, PGD, PGT, IUI, and ovulation induction. We have a highly experienced team of 50+ IVF specialists nationwide and an internationally trained team of embryologists. Additionally, we have state-of-the-art clinical and IVF labs for infertility testing and sensitive procedures such as ICSI. Thus, Australian Concept offers premier fertility services with a comprehensive, individualized approach and a comfortable and private environment.

How do I contact Australian Concept?

Dr. Sajjad’s Australian Concept Infertility Medical Center offers free online or on-clinic-first consultations with assisted reproductive technology (ART) coordinator doctors. These doctors take your complete history, order necessary testing, prepare your file, and direct you to a suitable IVF specialist according to your needs. Feel free to contact us at (0304-1112229 ) or visit today for the first free consultation.

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